Two and a Half Men Charlie Harper is a romance sim who has a new girlfriend every other day (by avarage). He lives in a Malibu beachhouse with 3 bedrooms and bathrooms, a large kitchen, two living rooms and two garages. He has a housekeeper Berta who does literally everything for him though she has quite a big mouth.
Charlie's little brother Alan has been married for 10 years, but is then kicked out of his house by his wife, Judith. They have a 9 year old son named, Jack. Jack is a real foodie and a bit slow at school. They live with Charlie after the divorce. Alan remaries once (or twice), but it always ends up in a divorce again.
Judith gets involved in a new relationship quite quickly after the divorce. It's the pediatrician of Jack, Herb Melnick. They get married and Judith gets pregnant again though it's not sure whether it's Herb's baby or Alan's (one adventure with Judith).
The brothers both have a love-hate relationship with their mother, Evelyn Harper. She has been married quite a few times. Always quite short. And she mostly inherits a lot of money. She's a real estate agent who mostly sells Malibu beachhouses.
There's of course more to it if you watch/know the entire series, but this gives a head start for a new sims game. | 
